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Sildenafil Citrate: The Erectile Dysfunction Drug That Changed the World

Sildenafil citrate is a medication that is used to treat erectile dysfunction (ED).

It is likewise used to deal with pulmonary arterial hypertension (PAH).

It works by relaxing the blood vessels within the penis, which lets in for better blood flow and an erection.

Sildenafil citrate is available as a tablet, capsule, or liquid.It is usually taken 30 minutes to 1 hour before sexual activity. The most common side effects of sildenafil citrate are headache, flushing, upset stomach, and stuffy or runny nose. More serious side effects can include heart attack, stroke, and priapism (a prolonged erection that is painful).

Sildenafil is not safe for everyone to take. It should not be taken by people who have certain heart conditions, such as high blood pressure or heart failure. It should also not be taken by people who are taking certain other medications, such as nitrates or alpha-blockers.

If you are considering taking this medication, discuss the risks and benefits with your doctor. They can help you decide if it’s right for you.


Here are some additional information:

  • Brand names: Viagra, Revatio
  • FDA approval date: 1998
  • Mechanism of action: Relaxes blood vessels in the penis, allowing for better blood flow and an erection
  • Dosage: 25-100 mg, taken 30 minutes to 1 hour before sexual activity
  • Side effects: Headache, flushing, upset stomach, stuffy or runny nose, heart attack, stroke, priapism
  • Interactions: Nitrates, alpha-blockers, other ED medications
  • Pregnancy category: C (not safe for use during pregnancy)
  • Lactation: Excreted in breast milk; not recommended for use while breastfeeding.